A third Premier League defeat of the season for Manchester United has changed the odds in the outright winner market, with Manchester City, Chelsea and Arsenal, as well as outsiders Tottenham Hotspur and Everton, all changing odds after an indifferent weekend for the top sides. At the bottom, Queens Park Rangers, Southampton and Reading are all odds-on for relegation, while Aston Villa, Norwich City and Reading are all still short prices for the drop.

United remain the favourites to win the Premier League title with bwin, but they have drifted after a 1-0 loss to Norwich City at Carrow Road. A third league defeat of the season for Sir Alex Ferguson’s men has seen them surrender top spot in the table and lengthen from 9/10 to 5/4 to win the title.

The new leaders are Manchester City, who thrashed Aston Villa 5-0 at the Etihad Stadium to go one point clear of their neighbours. The champions have hit the summit for the first time this season and are now 7/5 from 43/20 to reclaim their crown.

Chelsea remain in third place, and third favourites, despite losing 2-1 to West Bromwich Albion at the Hawthorns. Roberto Di Matteo’s side have gone from 13/4 to 4/1 to win the Premier League, while the Baggies, who are fourth in the table on 23 points after a superb start to the season, are as big as 2,000/1 to finish top of the pile.

Arsenal got their season back on track with a 5-2 demolition of north London rivals Tottenham at the Emirates and are now back into 40/1 (from 66/1) to win the league for the first time since 2004. Spurs, meanwhile, have gone from 100/1 to 150/1 after falling to eighth in the division.

Everton have also drifted to 150/1 (from 100/1) after losing their second match of the season, 2-1 to Reading at the Madejski Stadium. That result was the Royals’ first win of the campaign and has seen their odds for relegation go from 3/5 to 7/10.

Southampton and Queens Park Rangers are also priced up at 7/10 apiece for relegation after the former beat the latter 3-1 at Loftus Road in a vital match at the bottom. Both sides remain in the relegation zone, but QPR are rock bottom without a win all season and you could have got 7/5 on the R’s to be relegated before the weekend.

Aston Villa are the third team in the drop zone after their hammering at the Etihad and they are 7/4 (from 11/5) to be playing in the Championship next season. Norwich’s win over Man Utd has seen their odds for the drop go from 5/4 to 39/20 after they climbed five points clear of danger.

Wigan Athletic are two points above the relegation zone after losing 3-0 to Liverpool at Anfield and are now priced at 9/4, from 5/2, to be relegated.

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